Beilstein J. Org. Chem.2014,10, 2930–2954, doi:10.3762/bjoc.10.312
improved synthetic approaches.
Keywords: ds-DNAandds-RNAbinding; intercalation; minor groove binding; nucleic acids; organic synthesis; phenanthridine; phenanthridinium; Introduction
The search for therapeutic agents of the phenanthridine type has increased when the outstanding trypanocidal activity
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Graphical Abstract
Scheme 1:
The Grignard-based synthesis of 6-alkyl phenanthridine.